Pharmacology thiab Toxicology ntawm Hydroxypropyl Methyl Cellulose

Hydroxypropyl methylcellulose yog ib feem methyl thiab ib nrab polyhydroxypropyl ether ntawm cellulose, uas tuaj yeem yaj hauv dej txias los tsim cov kua dej khov. Nws cov khoom zoo ib yam li cov tshuaj viscoelastic (feem ntau mucins) hauv cov kua muag, thiab yog li ntawd, nws tuaj yeem siv los ua kua muag dag.
Nws cov txheej txheem ntawm kev txiav txim yog ua raws li lub ntsej muag ntawm lub qhov muag los ntawm kev adsorption ntawm polymers, simulating qhov kev txiav txim ntawm conjunctival mucin, yog li txhim kho lub xeev txo ntawm ocular mucin thiab ua kom lub qhov muag tuav lub sij hawm nyob rau hauv cov kev mob ntawm txo cov kua muag. Cov nyhuv adsorption no tsis nyob ntawm qhov viscosity ntawm cov tshuaj, yog li tso cai rau cov viscosity qis dua kom muaj cov nyhuv ntub dej tsis tu ncua. Tsis tas li ntawd, ua kom cov nyhuv ntub dej ntawm lub cornea los ntawm kev txo qhov kev sib cuag ntawm lub ntsej muag huv.